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April 10th, 2025
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INSA-LYON
evolutionary biology
biorxiv

Aevol-9: A simulation platform to decipher the evolution of genome architecture

Luiselli, J.Open in Google Scholar•Parsons, D.Open in Google Scholar•Galle, R.Open in Google Scholar•Banse, P.Open in Google Scholar•Rouzaud-Cornabas, J.Open in Google Scholar•Beslon, G.Open in Google Scholar

Aevol is a forward-in-time simulator of genome architecture. It simulates a population of individuals, each with an explicit genome whose sequence and architecture can be modified by various mutational operators, including substitutions, indels, and large-scale chromosomal rearrangements. This enables performing in silico experiments to decipher the effects of evolutionary conditions (e.g. population size, selection strength, mutation rates, and biases) on genome organization.

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