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May 9th, 2025
Version: 1
UNIL-CHUV, HES-SO
bioengineering
biorxiv

A-eye: Automated 3D Segmentation of Healthy Human Eyeand Orbit Structures and Axial Length Extraction

Barranco, J.Open in Google Scholar•Luyken, A. K.Open in Google Scholar•Stachs, O.Open in Google Scholar•Langner, S.Open in Google Scholar•Franceschiello, B.Open in Google Scholar•Bach Cuadra, M.Open in Google Scholar

This study addresses the need for accurate 3D segmentation of the human eye and orbit from MRI to improve ophthalmic diagnostics. Past efforts focused on small sample sizes and varied imaging methods. Here, two techniques (atlas-based registration and supervised deep learning) are tested for automated segmentation on a large T1-weighted MRI dataset. Results show accurate segmentations of the lens, globe, optic nerve, rectus muscles, and fat. Additionally, the study automates the estimation of axial length, a key biomarker.

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