2025 Hyper Recent •CC0 1.0 Universal

This work is dedicated to the public domain. No rights reserved.

Access Preprint From Server
July 17th, 2025
Version: 1
Université de Bretagne Occidentale: Universite de Bretagne Occidentale
genetics
biorxiv

A population genetic study of Fusarium graminearum, the causal agent of Fusarium Head Blight, provides insights into patterns of inoculum dispersal in wheat fields at a regional scale

NGUYEN, T. B. H.Open in Google Scholar•Le Floch, G.Open in Google Scholar•Henri-Sanvoisin, A.Open in Google Scholar•Treguer, S.Open in Google Scholar•Foulongne-Oriol, M.Open in Google Scholar•Picot, A.Open in Google Scholar

Fusarium graminearum is the primary pathogen responsible for Fusarium Head Blight (FHB) in cereals, causing yield losses and mycotoxin contamination. The present study investigated the genetic diversity and population structure of F. graminearum from wheat grains and maize residues, which were the primary inoculum sources of FHB. A total of 588 isolates from four different fields were genotyped using a sequence-based microsatellite genotyping method of 34 SSR markers (SSRseq) and characterized for chemotype distribution. The results revealed high genetic diversity with 453 distinct multilocus genotypes (MLGs) without significant genetic differentiation by geographic location or substrate, suggesting a single metapopulation at the regional scale. This absence of substrate genetic differentiation strongly supports the fact that residue-borne inoculum contributed to FHB infection, although we failed to demonstrate any field-specific dispersal pattern from residues to grains. The findings underscore the importance of maize residues as a critical inoculum source and highlight the need to consider both local and regional sources in FHB management.

Similar Papers

biorxiv
Fri Jul 18 2025
Sex-specific disease association and genetic architecture of retinal vascular traits
Sex as a biological variable (SABV) remains underemphasized in biomedical research, despite its well-established impact on disease prevalence, progression, and genetic architecture. Here, we investigated sex differences in retinal vascular phenotypes, which are emerging as non-invasive biomarkers for ocular, cardiovascular, and neurodegenerative diseases. We used both interaction and sex-stratifie...
Böttger, L.
•
Bontempi, D.
•
Trofimova, O.
•
Beyeler, M. J.
...•
Bergmann, S.
biorxiv
Thu Jul 17 2025
Branching architecture constrains the accumulation of somatic mutations in trees
Trees are long-lived plants that develop highly branched shoot systems over time. During growth, somatic mutations accumulate along these branching structures and can become fixed in reproductive tissues such as flowers and fruits. Because mature trees produce tens of thousands of terminal branches, each harboring potentially mutated gametes, limiting the accumulation of somatic mutations is criti...
Johannes, F.
biorxiv
Thu Jul 17 2025
A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating
An individual's phenotype reflects a complex interplay of the direct effects of their DNA, epigenetic modifications of their DNA induced by their parents, and indirect effects of their parents' DNA. Here, we derive how the genetic variance within a population is changed under the influence of indirect maternal, paternal and parent-of-origin effects under random mating. We also consider indirect ef...
Kraetschmer, I.
•
Robinson, M. R.
biorxiv
Thu Jul 17 2025
Effects of ancestry, agriculture, and lactase persistence on the stature of prehistoric Europeans
Ancient DNA has revolutionized our understanding of human evolutionary history, but studies focusing solely on genetic variation tell an incomplete story by neglecting phenotypic outcomes. The relationships between genotype and phenotype can change over time, making it desirable to study them directly in ancient populations rather than present-day data. Here, we present a large-scale integration o...
Cox, S. L.
•
Kaymak-Loveless, K.
•
Shin, C.
•
Alihodzic, T.
...•
Mathieson, I.
biorxiv
Thu Jul 17 2025
When does accounting for gene-environment interactions improve complex trait prediction? A case study with Drosophila lifespan
Gene-environment interactions (GxE) have been shown to explain a non-negligible proportion of variance for a plethora of complex traits in different species, including livestock, plants, and humans. While several studies have shown that including GxE can improve prediction accuracy in agricultural species, no increase in accuracy has been observed in human studies. In this work, we sought to inves...
Morgante, F.
•
Tiezzi, F.
biorxiv
Thu Jul 17 2025
Replication Timing Uncovers a Two-Compartment Nuclear Architecture of Interphase Euchromatin in Maize
Genome replication is temporally regulated during S phase, with specific genomic regions replicating at defined times in a process that is known as replication timing (RT). Based on 3D cytology in replicating nuclei, we previously proposed a mini-domain chromatin fiber RT model for maize euchromatin that suggested it is subdivided into early-S and middle-S compartments, distinguished by chromatin ...
Akram, H. S.
•
Wear, E. E.
•
Mickelson-Young, L.
•
Turpin, Z. M.
...•
Bass, H. W.
biorxiv
Wed Jul 16 2025
Dynamic convergence of neurodevelopmental disorder risk genes across neurodevelopment
Over three hundred and seventy-three risk genes, broadly enriched for roles in neuronal communication and gene expression regulation, underlie risk for autism spectrum disorder (ASD) and developmental delay (DD). Functional genomic studies of subsets of these genes consistently indicate a convergent role in neurogenesis, but how these diverse risk genes converge on a smaller number of biological p...
Fernandez Garcia, M.
•
Retallick-Townsley, K.
•
Pruitt, A.
•
Davidson, E.
...•
Brennand, K.
biorxiv
Wed Jul 16 2025
Chromosome Size as a Universal Predictor of Recombination Rate: Insights from Holocentric and Monocentric Systems
Recombination is a fundamental evolutionary process essential for generating genetic diversity, facilitating adaptation, and driving speciation. However, direct measurement of recombination rate remains challenging, as standard methods such as chiasma counts or genetic linkage mapsare labor-intensive and often infeasible for non-model species. In this study, we identify chromosome number and mean ...
Zedek, F.
•
Bures, P.
•
Elliott, T. L.
•
Escudero, M.
...•
Marques, A.
biorxiv
Wed Jul 16 2025
Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
The HOXA gene locus coordinates body patterning, hematopoiesis, and differentiation. While studying blood phenotype-associated variation within the HOXA locus, we identified a genetic variant, rs17437411, associated with globally reduced blood counts, protection from blood cancers, and variation in anthropometric phenotypes. We find that this variant disrupts the activity of a previously unstudied...
Lyu, P.
•
Agarwal, G.
•
Guo, C.-J.
•
Ye, T.
...•
Sankaran, V. G.